Reye-like syndrome following treatment with the pantothenic acid antagonist, calcium hopantenate.

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Reye-like syndrome following treatment with the pantothenic acid antagonist, calcium hopantenate.

Three senile patients developed fatal acute encephalopathy while receiving calcium hopantenate. The clinical, biochemical, and pathological picture was similar to Reye's syndrome. Calcium hopantenate is a pantothenic acid antagonist. The serum levels of calcium hopantenate were high in coma, and that of pantothenic acid examined in one patient was lowered. Evidence obtained indicated that the R...

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ژورنال

عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry

سال: 1988

ISSN: 0022-3050

DOI: 10.1136/jnnp.51.4.582